I handload on Dillon 550b for accuracy and safety:
38 Special,
357 Magnum,
357 Maximum,
44 Special,
44 Magnum
45 Colt
Quote from above:
"My favorite part of reloading (by far) is load development with a new caliber, bullet and/or powder. Guess it's the engineer in me but the systematic application of knowledge, theory and process to eat away at the unknowns cranks me up. " Me too.
I think most guys reload one caliber with one powder and one bullet. That's not me.
So I use 10 different powders and 6 different bullets for each of the 6 calibers. I use 6 different powder weights for each test lot.
10x6x6x6 = 2160 combos to test with of course, 6 shots each. This requires you to setup your dies thousands of times.
I set the brass holder, the primer size, and a powder.
I set the powder weight. I set the flare.
I set the seater die for the bullet length.
I set the crimp die.
I make 12 cartridges (save 6 for later), marksalot them, and then change bullets which means resetting the seater die 6 times for the 6 different bullets. Resetting the seater die required loosening the lock nuts and guessing how much to turn. Do this every couple of minutes.
This last step was driving me crazy until I got the Redding Competition Seating die which is fully finger adjustable from the top. It cost 5x what the others cost, but is worth every penny.
I then bump the powder charge by .25 grains and start over.
If I were to count the lubing techniques I'm going through, the possible combos count would skyrocket. I can only test about 50 combos a day. Only 300 rounds, but it takes time to shoot every shot for accuracy, measure, and record data.
After testing with 6 shots and saving 6 rounds, I now have a library collection of different cartridges for each caliber; different powders, different powder weights, and different bullets. I always test with the same "Reference Revolver". I meticulously record the testing including chronograph. But, everyone knows that different guns will NOT shoot the combos the same way. The Shooting Logs and the library can save you days of work trying to find that right combo for each firearm.
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I use 6 marked coffee cans while shooting to dump my brass in. That keeps the calibers separate which stopped the horrible steps of ground pickup and hand separating. Cases in cases gets ugly quick.