Bottom Line:
A: .357 Sig and .40 S&W should never have been born; they are solutions looking for a non-existent problem. Now here's the heresy: The .45 ACP should also never have been born. It doesn't do anything to a person that a 9mm won't do just the same. They talk about the Moros, but never tell you the sequel, which is, the .45 didn't work any better than .38, and some Moros weren't even stopped by the .30-40 Krag rifle round.
B: 9mm Parabellum is all you need for anti-personnel work. The rest of the world somehow gets by without noticing any lack of lethality.
C: Big pistol cartridges are quintessentially American. They are useful for hunting, bear defense, and certain types of competition, but no more. Dirty Harry would have been better served with a Model 10 in .38 spl than the Magnum.
D: Shot placement and penetration are 100%. There is no evidence that can be gleaned from people who have been shot, be they living or dead, that hollow points, trick bullets, faster bullets, lighter bullets, heavier bullets, have any discernible differential effects.
E. They survive who put the most bullets in vital areas of the bad guy. The corollary is that more shots available is good, and less recoil means faster shots, which is even better. The conclusion from this is that the best cartridge is one that gives adequate penetration with the least recoil.
F: Building from E, in revolvers that is the .38 spl. In semi autos it's the 9mm, with the added benefit that in the semi, you also get the benefit of more rounds available.
G: In .357 Sig, you get a 9mm hopped up about another 200 fps or so from 9mm Parabellum. Since both cartridges will drive a bullet of ordinary weight (115 to 147 grains) to a speed that will penetrate adequately, you get no gain, but give up more recoil (slower shooting) and magazine capacity (fewer shots).
H: Generalizing from F and G, if you're carrying more than a .38 spl or a 9mm for self-protection, and don't have some rare highly specialized reason to do so (example: doubling as bear defense), you are overpowered and may pay the price.