I did it for awhile with my P365XL and Holosun 407K/507K.
My thoughts on it are that it's absolutely doable, but just not ideal for me at the moment. The biggest gain I had was precision, which is why I have a dot on my target .22. I'm pretty decent with irons, but my groups and ability to hit smaller targets at longer ranges really improved.
I did have three issues with it. The first is the biggest issue I had, the lack of predictability of dot brightness. I didn't even think about it, but the first time I carried it to the range I'd set the brightness to a useable level indoors, and when I got to the outdoor range it was invisible. I adjusted the brightness for the range, got home, the dot is super bright and unusable. Unlike dots used on rifles, you don't really get a good chance to manually adjust your dot to changing light levels, since its presumably in your holster concealed and not being messed with. I'm sure there are options (and will be more) with decent auto-adjustment, but thats about the only fix I can figure out.
The second issue is getting crud into the window. The window acts like a scoop, not a big issue for most concealed use but you can definitely get sand, sweat, and lint in there if you're unlucky. It's not always a problem but definitely something I paid attention to.
The third issue is really not the fault of the dot at all, but where I noticed it. When you're using a rifle dot, you really don't need to think about where the dot will be, since placing your cheek on the stock gives you an extra contact point and aligns you pretty well. If you're off even a tiny bit on the pistol dot, you can't see it at all and are chasing it, whereas with irons you can at least quickly align your sights since both front and rear are visible even if you're not aligned. The correct answer to this is just get your presentations better and fix the sloppiness, but I didn't quite have the time and ammo during the covid panic to do so.
If you want to try a dot, there are lots of options out there, and they are definitely going to be the future. I'm seeing more and more cops with dots on their pistols both in person and in the footage we see, you'd still be an early-ish adopter but it's not some unproven tech.