I'm going to drift the thread further off track and ask what's the attraction to shotgun slugs for Sasquatch, oops, I mean bears? A typical 1 ounce 12 gauge slug is only about 435 grains. Many rifles fire heavier bullets and they give you the option of aiming for the nostrils. Is it just that shotguns are presumed to swing into action faster?
Here's my take for what it's worth. I have lived up here for 18 years and have been a firearms instructor for 15 of those years and have been a wildlife intervention trainer for the past 7 years.
In wildlife intervention scenarios, where a person is assigned the job of providing bear coverage for a work crew, they are required to have, by USFW regulations, force options other than lethal. I don't know of any rifles that can make the change from lethal, to less lethal to pyrotechnic deterrence with the ease and speed of a pump shotgun. In fact I have never seen less lethal or pyrotechnic rounds for rifles.
Stepping out of the professional world and into the civilian world one is certainly free to carry what ever they like . A 12 gauge slug is a formidable tool, but then so is a large bore rifle. You may however, find high power optics to be more of a hindrance than help when trying to find a bear's nostrils at 10 yards on 14 power. I have more than once reminded hunting partners to turn their mega scopes down to the lowest setting as we entered into thick stuff. Most set their scopes as high as they can and never change the setting. I would rather have an open sighted, large bore weapon, be it shotgun or rifle, were I to face down a charging bear. I've had a fair number of close encounters with bears, but fortunately all have ended amicably with neither of us leaking bodily fluids.
So as to no get too far off track on the OP's thread, what is the 10mm good for? The 10mm is a viable option for bear protection. I was in a couple shops today and the only handgun ammo I found was Buffalo Bore 10mm, 480 Ruger and 475 Linebaugh. Lots of 10mm bear stuff. I might personally choose a bigger gun but that's because I have them. I certainly wouldn't be afraid to go afield here with a heavily stoked 10mm.