I have 6 Ruger Vaquaros (2-44/40,4-45 colt)and a bunch of Colt clones in 45 including a Thunderer. I've made a shot shell out of 460 S&W cutdown to 45 Colt OAL, Taper the mouth about 3/16ths inch with a 44-40 sizer die. I use a SASS type of powder charge, cork over powder charge, 1/2 oz. of #7.5 shot, second cork card over shot, and seal case mouth. Seal with anything you like, but I use gutter seam sealer and let cure 2-3 weeks (glue,parifine,waterglass all crack out and the shot falls out). This load holds up to recoil. In my 5.5 inch Rugers it had a 12" patern at 12'. It is a chore making these shot shells but I didn't need to buy a Judge for a half ounce shell that fits the needs on the trail. This load shreaded a W Va copperhead at 10 feet in the fall of 2011. When I'm afternoon walking in the woods this load followed by my 230 LFN at 750 fps is in the single actions. On long backpacking trips it is an airweight 38 on the hip belt(as I got old I've tuned into some sort of wimp). Ivan