Yes full house loads have a purpose, especially in .357 Magnum. The problem with full power loads, are you talking today's loads or the old pre-K frame scorcher loads that were 160 grains and 1,500 fps plus from a longer barrel? If you go by the old school loads, then 1,250 fps is the middle of the road. I know I tested out some .357 loads in my 3 1/2 inch Model 27 last year, 125 grain Hornady XTP's and 16.5 grains 2400. The bullets expanded perfectly and stopped in 12 inches of wet newsprint. I think if you were to load those milder they might work great for personal defense. I am working on some 158 grain Speer Gold Dots for a hunting load and I hope they expand as well as advertised, that and my #358156 hollowpoints for whitetails. I am very interested to see how my .38-44 loads with those same Gold Dots expand. I test those in my 3 1/2 Model 27 because they help with some of the velocity loss with three inches of barrel difference between that 6 1/2 inch barreled Outdoorsman.
One little side note is that some bullet makers are listing the velocities where their hollowpoints expand. If I recall the XTP's don't expand until they get to 1,000 fps. I have been fun last year with my Outdoorsman and getting the alloy right with my own hollowpoints. The bullets that expand at 1,250 fps in my Outdoorsman did nothing in my standard or even some +P loads out of my 649. I shot a large woodchuck with my 649 and some of my cast hollowpoints and it was a neat hole in and a neat hole out the other side. I have some soft cast HP's I have yet to test and then some 125 grain Hydrashoks to see what they do.
Basically what you want to do with your gun determines what bullets and loads you are looking for. I like shooting .357 Magnum loads, even one handed the recoil does not bother me much with hotter stuff. I also have a heavier gun like my Model 27, if I had a K frame or L frame I would certainly notice it more and a J-frame would be nothing I would want to shoot my loads through for more than a cylinder or two. For personal defense I would say 1,250 fps would certainly expand with good hollowpoints, if you were hunting I would use a good 158 grain or better SWC, cast HP from the right alloy properly tested, or a good hunting HP like the Gold Dot. I tried even the 140 Leverlution or whatever Hornady calls it in my Model 27 and the expansion was zilch and the penetration was nearly two feet. I would get some good wet newspaper and test everything you carry, whether you hunt with it or not.
125 grain Hornady XTP's with 16.5 grains 2400 after 12 inches of wet newsprint.
150 grain #358156 HP's (50/50 soft lead and wheel weights) at about 1,200 fps after 15 inches in wet newsprint. Edges are very sharp on two outside bullets.