I currently hand-load for 32 acp, 380 acp, 7.65 mauser, 30 carbine, 38 spl, 357, 41 long colt, 38 long colt, 41 Magnum, 44 spl, 44 magnum, 45 acp, 45 auto rim, 45 Colt, 45 Colt (ruger Only), 454 Casull, 223, and 35 Remington. Those are all in handguns.
As Malpaso says" It's just a cool cartridge" (BTW, where in NE Washington are you? I'm in NCW) The 45 Colt is my "go to" cartridge because I LIVE AND WORK in grizzly country. I can get more for less in my Blackhawks. Oh, I currently have 3 Super Blackhawks and one 44 Mag OM Blackhawk. One of the NM SBH will be going to Gary Reeder soon for conversion to a 5-shot 454/45 Colt. I'll also be sending one off for my wife for conversion to 45 Colt.