I went ahead and bought both. The 460 with 45 Colt ammo is like shooting 38 wadcutters in the 66. The 500 I bought came with 40 rds of ammo, now all I have is 40 rds of brass. I'm waiting for my Starline brass to come in.
I started off thinking I'd want a 500. After some time thinking it over I realized I don't need to try to appear more manly with 500's and hummers, so I decided when the time comes, I'll grab a 460.
JK 500 and hummer fans... I'm just teasin!
In fact, I WOULD like both a 500 and 460...the 500.. well c'mon it's a 500! and the 460... something about those high velocities really appeals to me... hitting 2300 ft/sec makes me smile.
Also.. interestingly I have a large supply of .45 long.... but no .45 to shoot!
Really though, to pick one is tough... and not a decision that should be taken lightly. Each has great reasons to buy it.