I virtually never worry about what ammo is "best". I have a .40 S&W CZ-75 as my go to defensive weapon and sometimes I would leave the range with cheap target practice ammo it and I still had confidence it would do the job if needed for defense. If it had been a 9mm I would want some good +P JHP ammo to feel confident. For hunting, the cheap 12 ga. shotgun shells seem to work about as well as the high dollar stuff on duck, pheasant, and quail. For deer any .308/.270/30-06 ammo should group under 2-1/2" and that should be fine for any Whitetail under 200 yards. If I was taking 600 yard shots I might need some high grade accuracy but that doesn't interest me.
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