They are superb on deer at reasonable ranges and with decent shot placement.
This was about 10-11 years ago, and I was visiting Federal's factory in Anoka MN on another matter. While I was there, I stopped in to see the Federal ballistician. They were firing some .30-'06 Fusion loads into blocks of ballistic gelatin, and I pulled some of the fired bullets out with long tongs. Expansion was absolutely picture-perfect. I still have those bullets somewhere, but I haven't seen them for a long time.
I wonder why? Maybe all the new technology with lighter rifles, smaller caliber with more punch.