While the private citizen data base does show the average distance of an armed encounter to be 5 yards, the longest range has been 27 yards. For those of us of a certain age, that's a range where the optic really comes into it's own. Reduced light is another. Admittedly, if available, my first instinct at 27 yards is to get behind cover.
Also, for others "of a certain age", I've found a nice stainless front sight to be much better than the basic black sight.
Being of a certain age, I still prefer iron sights.
I teach people to bring the pistol up into their line of sight, place the front sight on target, and then pause to refine the sight picture and align the front sight with the rear sights, then hold that sight picture while they release the shot.
Over time and hundreds of repetitions the muscles in their hand "learn" to hold the pistol so that the sights are already aligned when the pistol comes up and the front sight is placed on target.
At that point any pause in the process is just to confirm the front sight is on target and or that the target still needs to be shot. For example if you just delivered a controlled pair center of mass, and are transitioning for a "failure to stop" head shot, but the target is now going down, a third shot is probably over kill.
From that perspective, and with tritium night sights installed, I just don't see any real advantage to having a red dot sight installed on self defense handgun.
A laser is even worse as it's taking the focus off the front sight and gets away from basic fundamentals that help you develop a grip that produces consistent sights alignment, unless you train to put the laser dot right on top of the front blade, which is just another form of sight alignment.
I also have a bit of an astigmatism in my left eye, a hold over from an altercation with an assailant and a broken cheek bone in my law enforcement days. That slight astigmatism results in a comma shaped dot and I get the effect when shooting with both eyes open, even though my right eye is dominant. It's a non issue at close range, but it is an issue for longer range precision shooting at 25 plus yards.