Handgun brass can be loaded until it splits. I have some .38 Special cases that have been reloaded so many times the nickel is worn off in spots. Even my heavy .44 Magnum loads go until the necks will split (I lost count at about 15 or 16 the last time I tried to keep track). I buy a lot of once fired brass in .38, .357, .44 Special and Magnum, 45 ACP and 9mm. I've found range pick-ups of about 1K of .223/5.56 and have no problems if I visually inspect each case...
I totally agree with mikld; as I only load for target practice (light/medium loads) if you just do a good job of inspecting each time you should not have any problems re-using until a crack or other deformity shows up.