I've not had the opportunity to fire the 327PD but I have shot the 329PD. For combat work I would use the Buffalo Bore LSWCHPGC 158grain +P which should be tripping along at just over 1000fps from a four inch. Accuracy is superior and energy and bullet design are legendary in profiecency for self defense.
Buffalo is spendy but very effective, they give a faster followup shot than 357 Mag ammo which is sometimes important. Iuse hand loaded +P rated 38s for practice and league.
Check em out at the Buffalo Bore web site.
I use them in my model 67 and 65 3" inch.