While it is some what dependent on ammo as a heavier bullet has more back pressure so more escapes at gap, powder burn rate etc. The longer the barrel the more time bullet is in it and the more tome gas had to escape. But from testing by "Ballistics by the Inch" a 4" shooting 158 grain lead SWC 357 gave at 10 shot average of 1197 with no gap at all, 1123fps with a .001 gap and 1104 with a .006 gap. A 6" with 0 gap got 1286, .001 got 1196 and .006 got 1178
So, You lose a bunch with just .001 gap then the amount of gap has way less effect. Because with a 4" the first.001 lost 75fps and the next .005 only lost 19fps only about 1/4 of what the first .001 lost. The 6" lost 90 fps with the first .001 then 18 fps opening the gap from .001 to .006. Of course a revolver will not function at all with .0000 gap and not for very well for long at .001.
It would be hard to convince me that the addition of another .004, making the gap a total of .010 would cost you more than another 10fps. Or that closing the gap to say .003 from .006 would can you more than 10fps. Most ammo has a velocity deviation greater than that.
I used to be more concerned about gap and prefer .004-.006 but after reading some actual testing I am not quite so worried about it.
I believe a good forcing cone is more important than the B/C gap.