It takes an extremely accurate rifle to benefit from uniforming primer pockets, deburring flash holes, neck turning and all that other stuff. Benchresters do it, but they measure their groups in hundredths of an inch, not in inches. Even most good varmint rifles won't notice the difference. I have never heard of a handgun demonstrating that it helps.
New brass, I resize it full length, chamfer and deburr case mouth and measure some for length. If they vary much, I'll trim the batch for uniformity unless they are already under trim-to length, or not uniform. Then I inspect them really well. Sometimes they slip through with no flash hole or something.
Uniform case length is important especially if you are going to crimp the case mouths into the bullets. Uneven lengths will vary the amount of crimp applied.
I trust my handloads, assembled in once-fired brass, to be more reliable and dependable than factory ammo. Having been shot once "proofs" the brass cases, letting you know if they have flaws or not.