When I started reloading I accumulated more than 20 different powders. When I started reloading again after a 40 year layoff, I researched the load manuals and came up with HP38, which had not even been created when I previously reloaded, nor had W231. I do have a can of W230P from back then.
I have used the HP38 for 9mm, 38, 357, 41 Mag, 45 Colt, 45 ACP and 38 Super. However, 99.9% of my loading is for 45 ACP and 38 Super, which I use to try to make holes in paper or knock over plates. I buy it by the 8# jug and once I find a load I like, that is what I set up for.
For MY purposes it does everything I need to do and keeps powder stocking and use simple. 8# of powder and 10K of primers just about even out.
This is where most of my old powder ended up: