I think that with lesser guns, the forcing cone is responsible for compensating for less than perfection in the barrel to chamber alignment.
Unfortunately, my new 66 snub has only the merest hint of a forcing cone. The new revolver shoots my hand loads well, but I was experiencing some kind of blowback when I fired my factory loaded Speer 135 gr GDSB MGN rounds that I was planning on using for EDC. I don't know if it was brass, lead or powder, but something was hitting my left cheek consistently with these cartridges. The gun is nice and tight, and the BC gap is what I consider an ideal .004 inch. BB non plus pee FBI load worked well. I have to shoot these clandestinely, since the range doesn't allow exposed lead bullets. The gas check does a good job of reducing smoke. When I shot the BB 150 gr hard cast WC's another time, the smoke gave me away and I got a warning. The lead police caught me on their TV system!
I plan to return to the range with some more loads on Thursday. With my Ahrends finger grove boot grips, the revolver feels just right for a "large" carry gun. My "small" EDC is a M640Pro, with the J frame version of the Ahrends boot grips.
Best,
Rick