I use the DeSantis most of the time for my 642, but sometimes I grab the Remora. The Remora has the advantage of being able to be carried as an IWB holster as well. Something about the material keeps it in place in your belt without clips or loops, and it really does stay put. But if I know that I am planning on carrying in my pocket all day I'll just go with the DeSantis. (I also have the Uncle Mikes, but as others have said, sometimes the holster comes out of the pocket with the gun when drawing, something much less likely with the DeSantis or the Remora.)