I'd say yes, the SD9VE makes a good first gun. I bought one a few months ago as my first striker fired gun. I have other semis, Sigs, 1911s, and CZs, but wanted to try a poly framed striker fired pistol.
My SD is reliable and has a grip that should be comfortable in most hands. (For me however, the CZ75 is the ergo winner by a long shot.). Thr SD has good and acceptable accuracy, but it's not a target pistol. The trigger has a long pull, similar to a revolver, but the trigger break took some getting used to. Some SD9 owners install a new trigger and spring. I'd try to get used to the stock trigger first.
The one thing I do not like about the SD series is the takedown, which is copied from the Glock. I prefer the Sig/Beretta takedown. With the Sig/Beretta system it's much easier to confirm the pistol is clear, you don't have to pull the trigger, and there are no fussy tiny tabs to pull down simultaneously. But, a lot of people have adapted to the SD/Glock takedown and regardless of the takedown fussiness my SD9VE is my current bedside pistol.
I'd suggest 9mm. Not a lot of recoil, inexpensive so you can shoot a lot, and you can find it almost anywhere. Plus there are good self defense loadings.