WHAT IS THE BEST .22 LR AMMUNITION FOR SELF DEFENSE?

I recall Bill Jordan saying the .22 has killed more folks than any other
caliber, excluding those killed in wars.
 
OK, given the OP is long gone the title still got my attention.

The answer is I wouldn't.

Yeah, with the right shot placement it will work but as an SD gun, just no. I do carry a 22 mag as my primary at times and even there it is more a belly gun to give me time to escape as the attacker winces or a show stopper if I can put it to his head or neck.

Sure you can practice more with a 22 but that is just general practice like working on trigger basics or other general shooting stuff.

Just my 2 cents on something I would bet doesn't come up often.
 
Thoroughly necro'd, but still fun.

Answer: "Whatever is most reliable." Which means CCI, Aguila, maybe Federal. The most important component is literally the primer compound. On cheap bulk .22, it's applied mechanically and very inconsistently, leading to some or even all of it drying and separating from the case, causing FTFs.
 
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