Which is more powerful? .45 or .357

A .357 magnum is clearly more powerful than .45 ACP. It also has much more penetrating capability - too much in some applications. Law enforcement seems to settle on 125 grain bullets, specifically to reduce penetration while delivering the same or higher muzzle energy as traditional 158 gr bullets. One exception may be state police, who are more likely to fire into vehicles through glass or steel.

Back when cars had steel bumpers (with chrome), I had occasion to use an abandoned bumper as a target. .357 SP would penetrate the bumper at any angle, and at least one shot left a hole 1/2" wide and 3" long. .45 ACP at the same target left big dents. Nor will a .45 penetrate a WWII steel pot helmet, per army training films.

It's questionable whether penetration power makes a good defensive load against soft targets. My preferred CCW is .45 ACP, not necessarily on a scientific basis. That load would be relatively ineffective against a tough target like a bear or hog. My woods handgun is .357 with 180 gr hard cast bullets, or .44 mag with 300 gr hard cast. They'd still work on a soft target, maybe two or three enfilade.
 
Since no one else has mentioned the obvious. The real answer is the one you can control, and effectively put on target.

Yeah, but that means you have to go the range and realistically practice: firing double action (depending on type of pistol), drawing from a holster, moving and shooting from cover, shooting on the move, shooting multiple targets, shooting one-handed, shooting weak-handed, using a timer to see what techniques really work, shooting from 1 to 25 yards, etc.

It's so much easier to just choose a magic bullet, caliber, gun, etc.
 
Here's my opinion:

I would consider the .357 Magnum to be more powerful. With that said, I have no interest in carrying it for self defense. The reason for that is the negatives outweigh the positives.

1. Flash from a .357 Magnum is tremendous, and at night, will be blinding. (Source: http://www.mcrgo.org/mcrgo/photo_gallery/people_blast/mb1.jpg )

2. The sound pressure created by a .357 Magnum round is about 5 times higher than that created by a .45 caliber round. Firing a .357 Magnum indoors whether you hear it or not, will mean you seriously damage your hearing. Period. There is indeed a "flash-bang effect" in play, imho. A .45 is still loud and painful, but less damaging by a fair amount (Source: FreeHearingTest.com - Gunfire Noise Levels ).

3. As already mentioned, follow-up shots are more difficult with a .357 Magnum.

Those are three main points I can think of off of the top of my head.
 
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