The absolute best advantage for this round is what it can be chambered in. AR, compact bolt action, and now a revolver. Secondly, recoil reduction. Wife has a slight build, and loves to hunt deer. At the NRA show she hefted several bolt guns in the new 350. Purchased a Ruger compact in 350, it has been turned into Psuedo Scout rifle for her. The one she REALLY liked was the Winchester XPR compact model. It was a bit harder to find and took awhile to locate but it's her favorite of the two. She doesn't have an AR chambered in it as of yet, and I do not believe she will.
First season she hunts with the XPR a hot doe walks into the feeder, one 170 grain bullet and the doe runs 25 yards and falls over dead. 20 minutes later a nice buck walks in trailing and one shot and the buck falls dead in place.
Second season a doe comes out of the woods, one shot and the doe falls dead in place. All 3 rounds pass completely thru, breaking ribs on the way in and on the way out. None recovered, but they did the job well.
Could she shoot the vaunted 38-55? Yes, but it would hurt her. The .375? Yes but it could hurt her more. And without major stock work, neither of those standard rifles would fit her.
It works well in the intended niche.
Regards from the Commonwealth,
Rick Gibbs
PS: No, she won't be buying this monster size revolver as a companion pistol…