Not often, but I have and will again. I'm comfortable with my three, I shoot them well, and that big ol' .45 Colt or .44 Mag just seems right at times. By the way, one of mine is the Uberti Schofield. It loads and unloads about as fast as most double action revolvers. One is the Berretta Stampede (Colt SAA clone) which points like nothing else for those "up close and personal" moments, and the other is a Ruger Super Blackhawk.
I'm not sayin' there the best choice or even the wisest choice for most folks; just a choice that I make from time to time. It is, afterall, my choice - isn't it?
By the way, those two are awfully nice Dave.