"Best" is personal. What's best for some isn't for others.
For my family access first floor hidden gun, I use Hornady Critical Defense 38 Special 110gr (NOT the +P) because the gun is there for my wife and daughter as well as me.
The 38 I carry a lot currently has Lehigh XD bullets loaded by Black Hills. I also like the 135 gr. GD, but all I have of those are my hand loads, and I generally prefer to carry a factory-produced rd.
Since nothing expands well 100% of the time from a snubby, I see the wisdom in carrying 148 gr. WC, especially ones with higher velocity, but I have never carried them. A few years from now, if I develop hand arthritis, they might be my EDC. 148 gr. WC penetrate well and have far less recoil than any common commercial defensive ammo.