If you like a Glock, then you'll really like the Ruger SR series. I own both, and strongly prefer the grip ergonomics of the Ruger to the Glock.
I have my SR9 set up with the "flat" side of the grip backstrap facing outwards, and it feels almost as good in my hand as a 1911 (and that's the ultimate semi-auto pistol compliment, IMHO

).
I don't use the manual safety of the SR9 since it also has a "safe action" trigger like the Glock, but it's there if you like it. The SR9 also has a loaded chamber indicator which I've found useful when using the SR9 in training sessions for new shooters.
Anyway, not knocking the Glock family, but seriously, I think Ruger really improved on it.
Lou