A P365/Hellcat competitor seems likely. I can imagine them making a new M&P Shield with a slightly longer/thicker grip to hold 10 rounds in the magazine, then just stamp a "3.0" on the slide along with some real front slide serrations and an optics mount for good measure.
It's a safe move for them to make since not only are the P365/Hellcat extremely popular as is, but they have the potential to be even more popular in the event that certain politicians get their way and the AWB makes a comeback, so it's a risk-free move that can only be profitable. Heck, if they offer it in .40 S&W and .45 ACP, then they'll have a portion of the market cornered since the P365/Hellcat are 9mm only.
The only way I see them doing a PCC is with a modified M&P15 Sport, I doubt they'd go all in on a market that could go belly up with the stroke of a pen by designing a unique PCC, unless of course it has been in development for some time now and the money has already been spent on R&D.
M&P10mm? Not happening. They haven't made a 10mm Auto pistol since 1994, and for good reason, it would cannibalize sales of the .40cal pistols at best, flop altogether at worst. High risk, low reward.