Most people, in decades past, before reliable semi-autos, were often told by gun dealers, that the snubbies, (model 36, 60, Colt D.S., Agent, Cobra), were great home defense guns, if they only had interest in having one gun.
We now know, that wasn't neccessarily, the best advice, and most people, (before ccw), were better served by the K frames, or similar sized guns, for the home.
Now, with all of these states with ccw permits, things have changed alot, and the 642, and 638, etc. are very popular.
Personally, though it isn't the best looking gun around, I think the models 38, 49, and 638, offer the best compromise, of concealment, and less chance of snagging on clothing, while retaining the single action option.