I have to say, the number of people who "have never had an ammunition failure in their xx years of reloading" is absolutely hilarious.

Maybe I am lucky .. or unlucky depending who you ask but .. I have fired CASES upon CASES upon cases of factory ammo over nearly 4 decades in .38, .380, 357, .45, .40 .9, 10mm, 44mag, 44 special and even a few hundred 45lc and 12 guage. Bought from all different manufacturers.
In tens of thousands of rounds I have never had one not fire.
My reloads ... I have maybe reloaded about 3000-4000 rds .. 2 fails to fire and more than a few keyholed inaccurate rounds because of a crimp that was too tight.
I just like the math best for using Factory for my SD.
Buy it .. shoot a few to make sure they work .. stick it in the closet. It may seem expensive but since you will probably go to your grave with out having to shoot anyone you only need a couple of boxes.
I still have some boxes of 9mm SD ammo from I think the early 90's sitting in an ammo can. Probably should just go shoot it. Guess I would need a 9mm handgun though!!
I swear I dont know where the myth of reloading "killer" ammo and its implications in a self defense shooting started but even before the internet it was a erroneous assumption.
I know I wont convince anyone who has made up their mind already but .. if god forbid you shoot someone in defense of yourself or a loved one within the laws of self defense in your state then the only thing that will be in question is whether you were indeed justified in using deadly force and not the manner in which you inflicted death. Stab him with a kitchen knife, hit him with a bat, scare him to death by running out of the shower nude ... doesnt matter.
Were you justified in using deadly force?
Now a Jury is made up of your peers and some of our peers are gun people and some not and some are smart and some are not and they all come with different make ups. Can/will a prosecutor, hot to convict you, use information that in the end is not relevant to try and color a juror. Of course! and once heard you cant unhear but any defense attorney worth peanuts will object every time the discussion veers from "was justifiable force used.
Let me add one more thought just for conversation .. if indeed rolling "more lethal" rounds was a deciding factor in your shooting .. couldn't then a person be faulted for using a .357 or a 44 mag instead of a 22 or 9mm because the person chose the .357 (or round of your choice) because it was reported to me MORE lethal. Of course not .. well maybe they could use it to color a juror but since there is no legislation against the use of those rounds in a self defense situation you cant be tried or found guilty of it.
So much was made about Fish and his 10mm. I carry 10mm often. It wasnt the 10mm that got him sent to jail (later acquitted) it is what flavored the news because the prosecutor wanted it to be color. If you look it up carefully there were some inconsistencies in his story and time line and his jurors had trouble with it. He was never sent to jail because he used a 10mm.
I try and keep in mind that a self defense shooting is THE LAST RESORT! If you arent sure if you are at the last resort then don't shoot. If you are .. and you know you had no choice but to take a life then what round you used is irrelevant.
I do stay away from gun doodads that speak to a militaristic mind set. A jury may see your gun in evidence 20 times. If it has punisher symbols or colorful sayings and its holstered in that extra special skull motiff holster .. well .. the jury is your peers and are human. If the shoot is close to borderline it might show a mindset but then still the question is was it a good shoot and not the doodads.