When I started hand loading, I used Unique for most of my cast lead projectiles. A few decades ago, I switched to 231. The 231 produces less smoke when burning the bullet lube.
My favorite plinking load is a 158 grain hard cast SWC over 5.5 grains of 231
H110 has been my goto Full Power Magnum powder since the 70s. Back then it was a fairly NEW powder on the market
My favorite jacketed load is a IMI 125 JSP over 21.6 grains of H110
These have both been shot in everything from J-frames to lever guns.
The jacketed load always makes an impression when fired from one of the 2 1/2" Model 19/66s
No matter what the power level, I alwasy load ammunition that I intend to shoot in 357 Magnum firearms, into 357 Magnum casings